| Primary Identifier | MGI:2681162 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 224480 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables heme binding activity and superoxide-generating NAD(P)H oxidase activity. Acts upstream of or within detection of gravity; otolith development; and temperature homeostasis. Located in cytoplasm and plasma membrane. Part of NADPH oxidase complex. Is expressed in inner ear. Orthologous to human NOX3 (NADPH oxidase 3). PHENOTYPE: Homozygous mutants bilaterally lack otoliths in otherwise normal ears and display impaired swimming ability, motor capabilities, and vestibular responses. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
