Primary Identifier | MGI:1920347 | Organism | mouse, laboratory |
Chromosome | 17 | NCBI Gene Number | 240025 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables several functions, including beta-catenin binding activity; delta-catenin binding activity; and protein kinase C binding activity. Involved in several processes, including epithelial cell morphogenesis; inner medullary collecting duct development; and negative regulation of nodal signaling pathway. Acts upstream of or within hematopoietic progenitor cell differentiation. Located in mitochondrion. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; sensory organ; and umbilical vein. Orthologous to human DACT2 (dishevelled binding antagonist of beta catenin 2). PHENOTYPE: Mice homozygous for a knock-out allele develop normally but display enhanced keratinocyte migration and accelerated re-epithelialization during cutaneous wound healing. [provided by MGI curators] |