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Protein Coding Gene : Spaca6 sperm acrosome associated 6

Primary Identifier  MGI:1922452 Organism  mouse, laboratory
Chromosome  17 NCBI Gene Number  75202
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Involved in fusion of sperm to egg plasma membrane involved in single fertilization. Located in acrosomal vesicle. Orthologous to human SPACA6 (sperm acrosome associated 6).
PHENOTYPE: Mice homozygous for a transgene insertion that inactivates this gene exhibit impaired fertilization and male infertility. Mice homozygous for a null allele show male infertility due to inability of spermatozoa to fuse with the oocyte membrane. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 4930546H06 gene,
  • RIKEN cDNA B230206P06 gene,
  • 4930546H06Rik,
  • Spaca6,
  • sperm acrosome associated 6,
  • Ncrna00085,
  • B230206P06Rik,
  • MGI:1926095,
  • non-protein coding RNA 85

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Genome

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1 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

Homology

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Gene --> Protein-Protein Interactions

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Disease

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