Primary Identifier | MGI:3040700 | Organism | mouse, laboratory |
Chromosome | 17 | NCBI Gene Number | 332221 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA-binding transcription factor activity and sequence-specific DNA binding activity. Involved in negative regulation of DNA-templated transcription. Located in nucleus. Is expressed in several structures, including early conceptus; genitourinary system; gut; limb mesenchyme; and nervous system. Orthologous to human ZSCAN10 (zinc finger and SCAN domain containing 10). PHENOTYPE: Mice homozygous for a gene trap allele exhibit a pleiotropic phenotype including reduced weight, mild hypoplasia in the spleen, heart and long bones, eye malformations including microphthalmia, altered platelet counts, an activated immune status, and behavioral alterations. [provided by MGI curators] |