Primary Identifier | MGI:1916698 | Organism | mouse, laboratory |
Chromosome | 17 | NCBI Gene Number | 57256 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables serine-type endopeptidase activity. Predicted to be involved in proteolysis and spermatogenesis. Located in membrane. Is expressed in ovary; secondary spermatocyte; and testis. Orthologous to human PRSS21 (serine protease 21). PHENOTYPE: Mice homozygous for one knock-out allele impaires fertilization of epididymal sperm only in an in vitro experiment. Mice homozygous for another knock-out allele exhibit defective sperm maturation during passage through the epididymis and decreased spermfertilization capability. [provided by MGI curators] |