| Primary Identifier | MGI:1890662 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 65962 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables phosphatase binding activity. Acts upstream of or within negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction and sensory perception of sound. Located in several cellular components, including apical plasma membrane; nucleus; and stereocilium. Is expressed in atrioventricular valve; cochlea epithelium; organ of Corti; and semilunar valve. Orthologous to human NHERF2 (NHERF family PDZ scaffold protein 2). PHENOTYPE: Mice homozygous for a null allele are viable, fertile and overtly normal and display normal cAMP- and cGMP-activated CFTR transepithelial chloride transport and bicarbonate secretion in the small intestine. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
