Primary Identifier | MGI:105110 | Organism | mouse, laboratory |
Chromosome | 17 | NCBI Gene Number | 16898 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) A structural constituent of ribosome. Acts upstream of or within cellular response to interleukin-4. Part of cytosolic small ribosomal subunit. Is active in synapse. Is expressed in embryo; liver; and retina outer nuclear layer. Orthologous to human RPS2 (ribosomal protein S2). PHENOTYPE: Mice homozygous for an allele with a point mutation die prior to weaning. Mice heterozygous for the allele exhibit reduced body fat, mild muscle weakness, and increased circulating creatine kinase level. [provided by MGI curators] |