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Protein Coding Gene : Msrb1 methionine sulfoxide reductase B1
Primary Identifier  MGI:1351642 Organism  mouse, laboratory
Chromosome  17 NCBI Gene Number  27361
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables actin binding activity; peptide-methionine (R)-S-oxide reductase activity; and zinc ion binding activity. Involved in actin filament polymerization; innate immune response; and protein repair. Located in cytoplasm and nucleus. Colocalizes with actin cytoskeleton. Is expressed in extraembryonic component; genitourinary system; heart; inner ear; and skeletal muscle. Orthologous to human MSRB1 (methionine sulfoxide reductase B1).
PHENOTYPE: Mice homozygous for a gene trap allele exhibit oxidative stress. [provided by MGI curators]
  • synonyms:
  • Msrb1,
  • SelR,
  • D17Wsu82e,
  • selenoprotein X 1,
  • Sepx1,
  • Sepr,
  • selenoprotein R,
  • MGI:106283,
  • DNA segment, Chr 17, Wayne State University 82, expressed,
  • methionine sulfoxide reductase B1,
  • MGD-MRK-33975
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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

Homology

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Interactions

2 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

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Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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