Primary Identifier | MGI:3039635 | Organism | mouse, laboratory |
Chromosome | 17 | NCBI Gene Number | 407831 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within lymph vessel development; regulation of vascular endothelial growth factor receptor signaling pathway; and smooth muscle cell differentiation. Located in plasma membrane. Is expressed in several structures, including branchial arch; cardiovascular system; intestine; limb; and limb bud. Orthologous to human TMEM204 (transmembrane protein 204). PHENOTYPE: Homozygous null mice have enlarged lymphatic vessels with an abnormal smooth muscle cell coating. [provided by MGI curators] |