Primary Identifier | MGI:2670967 | Organism | mouse, laboratory |
Chromosome | 17 | NCBI Gene Number | 215001 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable receptor antagonist activity and transforming growth factor beta binding activity. Acts upstream of or within muscle cell development; roof of mouth development; and skeletal system development. Located in extracellular region. Is expressed in several structures, including adipose tissue; genitourinary system; lung; skeletal muscle; and spleen. Orthologous to human WFIKKN1 (WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1). PHENOTYPE: Mice homozygous for a null mutation show partial penetrance of posteriorly directed homeotic transformations throughout the axial skeleton, impaired muscle regeneration and a mild decrease in skeletal muscle weight in males. [provided by MGI curators] |