| Primary Identifier | MGI:1351341 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 268934 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable adenylate cyclase inhibiting G protein-coupled glutamate receptor activity; calcium-dependent protein binding activity; and calmodulin binding activity. Involved in presynaptic modulation of chemical synaptic transmission. Acts upstream of or within chemical synaptic transmission and learning. Located in neuron projection. Is active in cerebellar granule cell to Purkinje cell synapse; parallel fiber to Purkinje cell synapse; and presynaptic active zone membrane. Is expressed in central nervous system; dorsal root ganglion; foot; sensory organ; and skeleton. Orthologous to human GRM4 (glutamate metabotropic receptor 4). PHENOTYPE: Homozygous mutation of theis gene results in impaired motor learning, and reduced paired-pulse facilitation and post-tetanic potential. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
