Primary Identifier | MGI:104638 | Organism | mouse, laboratory |
Chromosome | 17 | NCBI Gene Number | 21786 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable identical protein binding activity. Involved in regulation of glucose metabolic process. Located in secretory granule. Is expressed in several structures, including alimentary system; integumental system; metanephros; nervous system; and sensory organ. Orthologous to human TFF3 (trefoil factor 3). PHENOTYPE: Homozygous mutation of this gene results in impaired intestinal mucosal healing and death from colitis after administration of dextran sulfate sodium. Mice show poor epithelial regeneration after injury. [provided by MGI curators] |