Primary Identifier | MGI:1921793 | Organism | mouse, laboratory |
Chromosome | 17 | NCBI Gene Number | 208292 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; brain; branchial arch; cardiovascular system; and genitourinary system. PHENOTYPE: Mice homozygous for a null mutation display prenatal and preweaning lethality with reduced growth. Mice heterozygous for one null mutation display retinal abnormalities. Mice heterozygous for a second allele display reduced lifespans with hepatosteatosis. [provided by MGI curators] |