| Primary Identifier | MGI:1888999 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 57875 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables enzyme inhibitor activity. Involved in negative regulation of apoptotic process; negative regulation of lipoprotein lipase activity; and triglyceride homeostasis. Acts upstream of or within negative regulation of endothelial cell apoptotic process. Located in extracellular space. Is expressed in several structures, including central nervous system; genitourinary system; heart; hemolymphoid system gland; and integumental system. Orthologous to human ANGPTL4 (angiopoietin like 4). PHENOTYPE: Mice homozygous for disruptions in this gene display decreased levels of triglycerides and cholesterol and a lower increase in body fat after exposure to gut microbiota. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
