| Primary Identifier | MGI:1860076 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 54197 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable identical protein binding activity; ubiquitin protein ligase activity; and ubiquitin-like protein conjugating enzyme binding activity. Acts upstream of or within several processes, including negative regulation of autophagy; protein destabilization; and regulation of autophagosome assembly. Located in membrane. Is expressed in several structures, including limb; nervous system; testis; and urinary system. Orthologous to human RNF5 (ring finger protein 5). PHENOTYPE: When subjected to muscle damage by cardiotoxin treatment, mice homozygous for a targeted null mutation display attenuated muscle regeneration associated with a delayed ER stress response. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
