| Primary Identifier | MGI:1932075 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 55979 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables 1-acylglycerol-3-phosphate O-acyltransferase activity. Acts upstream of or within phosphatidic acid biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system; and integumental system. Orthologous to human AGPAT1 (1-acylglycerol-3-phosphate O-acyltransferase 1). PHENOTYPE: Mice homozygous for a null allele show postnatal and premature death, reduced body weight and total body fat, decreased plasma leptin, glucose and IGF-1 levels, reduced gluconeogenesis, infertility, arrest of male meiosis, ovulation and estrous cycle anomalies, hyperactivity and audiogenic seizures. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
