| Primary Identifier | MGI:3505689 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 386463 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein homodimerization activity. Predicted to be involved in several processes, including amyloid fibril formation; corneocyte desquamation; and negative regulation of cornification. Predicted to be located in desmosome. Is expressed in skin. Human ortholog(s) of this gene implicated in alopecia; hypotrichosis 2; and peeling skin syndrome 1. Orthologous to human CDSN (corneodesmosin). PHENOTYPE: Mice homozygous for a null mutation display neonatal lethality with epidermal detachment. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
