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Protein Coding Gene : Rcan2 regulator of calcineurin 2

Primary Identifier  MGI:1858219 Organism  mouse, laboratory
Chromosome  17 NCBI Gene Number  53901
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0)

Predicted to enable calcium-dependent protein serine/threonine phosphatase regulator activity. Acts upstream of or within several processes, including calcineurin-NFAT signaling cascade; locomotion involved in locomotory behavior; and short-term memory. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; immune system; liver; retina; and stomach. Orthologous to human RCAN2 (regulator of calcineurin 2).
PHENOTYPE: Mice homozygous for a knock-out alle exhibit decreased body weight and resistance to diet-induced obesity, steatosis, glucose intolerance, and insulin sensitivity. [provided by MGI curators]
  • synonyms:
  • ZAKI-4,
  • Dscr1l1,
  • Down syndrome critical region gene 1-like 1,
  • MCIP2,
  • regulator of calcineurin 2,
  • Csp2,
  • Rcan2

Features --> Cross References

Genome

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0 Exons

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0 Involved In Mutations

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0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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1 Driver For