| Primary Identifier | MGI:1927073 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 63959 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables neurotransmitter transmembrane transporter activity; purine nucleoside transmembrane transporter activity; and uridine transmembrane transporter activity. Involved in neurotransmitter uptake and nucleoside transport. Acts upstream of or within nucleoside transport. Is active in plasma membrane. Is expressed in several structures, including central nervous system; hemolymphoid system; hindlimb phalanx; liver; and skeletal musculature. Used to study alcohol dependence and diffuse idiopathic skeletal hyperostosis. Orthologous to human SLC29A1 (solute carrier family 29 member 1 (Augustine blood group)). PHENOTYPE: Mice homozygous for a targeted null allele exhibit a slightly decreased body weight, increased alcohol preference and alcohol consumption, and reduced hypnotic and ataxic responses to ethanol associated with a reduction in adenosine tone. Adenosine uptake is almost completely abolished in mice homozygous for a knock-out allele. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
