| Primary Identifier | MGI:2146838 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 106565 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables identical protein binding activity. Involved in regulation of fat cell differentiation. Acts upstream of or within negative regulation of Notch signaling pathway. Predicted to be located in membrane. Is expressed in several structures, including alimentary system; brain; limb mesenchyme; metanephros; and musculoskeletal system. Orthologous to human DLK2 (delta like non-canonical Notch ligand 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased anxiety and depressive-like behaviors, altered vulnerability to restraint stress, and an impaired behavioral response to the anxiolytic action of alprazolam. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
