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Protein Coding Gene : Cul9 cullin 9

Primary Identifier  MGI:1925559 Organism  mouse, laboratory
Chromosome  17 NCBI Gene Number  78309
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable several functions, including ATP binding activity; ubiquitin protein ligase binding activity; and zinc ion binding activity. Predicted to be involved in microtubule cytoskeleton organization; protein ubiquitination; and regulation of mitotic nuclear division. Predicted to be located in cytosol. Predicted to be part of cullin-RING ubiquitin ligase complex. Is expressed in several structures, including brain; hemolymphoid system gland; muscle tissue; retina nuclear layer; and testis. Orthologous to human CUL9 (cullin 9).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased body weight, increased incidence of tumors, and decreased cellular sensitivity to radiation-induced apoptosis. [provided by MGI curators]
  • synonyms:
  • Cul9,
  • Parc,
  • cullin 9,
  • 1810035I07Rik,
  • p53-associated parkin-like cytoplasmic protein,
  • RIKEN cDNA 1810035I07 gene,
  • mKIAA0708

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Genome

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

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Disease

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