Primary Identifier | MGI:1926879 | Organism | mouse, laboratory |
Chromosome | 17 | NCBI Gene Number | 63856 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein heterodimerization activity. Acts upstream of or within inner cell mass cell proliferation. Predicted to be located in nucleoplasm and perinuclear region of cytoplasm. Predicted to be part of transcription factor TFIID complex. Is expressed in several structures, including Harderian gland; brain; early conceptus; genitourinary system; and tongue. Orthologous to human TAF8 (TATA-box binding protein associated factor 8). PHENOTYPE: Embryos homozygous for a gene trap mutation die at E4.0 and exhibit apoptosis of inner mass cells. [provided by MGI curators] |