| Primary Identifier | MGI:1343178 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 11811 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables cytidine deaminase activity. Acts upstream of or within cytidine to uridine editing and mRNA modification. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including head mesenchyme; lower urogenital tract; reproductive system; urethra epithelium; and vertebral axis musculature. Orthologous to human APOBEC2 (apolipoprotein B mRNA editing enzyme catalytic subunit 2). PHENOTYPE: Mice homozygous for a gene trapped allele display growth retardation and decreased bone mineralization and density. Mice homozygous for a knockout allele exhibit reduced body mass and a shift in muscle fiber type and develop a mild myopathy as as they age. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
