| Primary Identifier | MGI:1098238 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 319991 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ATP hydrolysis activity; microtubule binding activity; and microtubule motor activity. Predicted to be involved in microtubule-based movement. Predicted to be located in male germ cell nucleus. Predicted to be part of kinesin complex. Predicted to be active in cytoplasm and microtubule. Is expressed in lateral ventricle choroid plexus and metencephalon part of 4th ventricle choroid plexus. Human ortholog(s) of this gene implicated in artery disease (multiple) and type 2 diabetes mellitus. Orthologous to human KIF6 (kinesin family member 6). PHENOTYPE: Mice homozgyos for an ENU-induced allele exhibit normal exercise capacity and cardiac function. Mice homozygous for a knock-out allele exhibit premature death, hydrocephaly, dilated brain ventricles and defective ependymal cell cilia formation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
