| Primary Identifier | MGI:1342328 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 13164 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables identical protein binding activity; mRNA 3'-UTR binding activity; and translation activator activity. Involved in positive regulation of translational initiation. Acts upstream of or within female meiosis II; oocyte maturation; and positive regulation of meiotic nuclear division. Located in cytoplasm; nucleus; and ribosome. Is expressed in several structures, including central nervous system; early embryo; gonad; mesonephros; and sensory organ. Orthologous to several human genes including DAZL (deleted in azoospermia like). PHENOTYPE: Males homozygous for a targeted null mutation exhibit sterility with a complete absence of mature germ cells. In mutants, few spermatogonia enter meiosis, and those that do fail to proceed beyond pachytene. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
