Primary Identifier | MGI:2146808 | Organism | mouse, laboratory |
Chromosome | 17 | NCBI Gene Number | 224902 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable identical protein binding activity and sequence-specific DNA binding activity. Acts upstream of or within Sertoli cell differentiation and regulation of androgen receptor signaling pathway. Predicted to be located in nuclear body. Predicted to be active in nucleus. Orthologous to human SAFB2 (scaffold attachment factor B2). PHENOTYPE: Male homozyous mutant mice exhibit an increase in testis weight and an increased number of Sertoli cells. [provided by MGI curators] |