Primary Identifier | MGI:2159342 | Organism | mouse, laboratory |
Chromosome | 17 | NCBI Gene Number | 224938 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein kinase A catalytic subunit binding activity; protein kinase A regulatory subunit binding activity; and ubiquitin protein ligase activity. Predicted to be involved in several processes, including long-term memory; regulation of macrophage activation; and regulation of signal transduction. Predicted to be located in centriolar satellite; intermediate filament cytoskeleton; and plasma membrane. Predicted to be active in cytoplasm. Is expressed in heart ventricle; male reproductive gland or organ; nervous system; and skeletal muscle. Orthologous to human PJA2 (praja ring finger ubiquitin ligase 2). PHENOTYPE: Mice homozygous for a null allele exhibit epithelial and vascular alterations in kidney tissue. [provided by MGI curators] |