| Primary Identifier | MGI:1915867 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 68617 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables microtubule binding activity and protein homodimerization activity. Involved in establishment or maintenance of epithelial cell apical/basal polarity; microtubule bundle formation; and positive regulation of protein targeting to membrane. Located in several cellular components, including apicolateral plasma membrane; cytoskeleton; and lateral plasma membrane. Is expressed in several structures, including alimentary system; cranial ganglion; limb segment; metanephros; and neural ectoderm. Orthologous to human MTCL1 (microtubule crosslinking factor 1). PHENOTYPE: Global or Purkinje cell-specific homozygous knockout affects Purkinje cell axon and dendrite morphology, resulting in abnormal motor function. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
