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Protein Coding Gene : Tgif1 TGFB-induced factor homeobox 1
Primary Identifier  MGI:1194497 Organism  mouse, laboratory
Chromosome  17 NCBI Gene Number  21815
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables chromatin binding activity. Acts upstream of or within several processes, including negative regulation of retinoic acid receptor signaling pathway; positive regulation of amacrine cell differentiation; and regionalization. Located in nucleus. Is expressed in several structures, including alimentary system; brain; early conceptus; embryo ectoderm; and genitourinary system. Used to study otitis media. Human ortholog(s) of this gene implicated in holoprosencephaly and holoprosencephaly 4. Orthologous to human TGIF1 (TGFB induced factor homeobox 1).
PHENOTYPE: Homozygous null mice display normal growth, behavior and fertility. [provided by MGI curators]
  • synonyms:
  • expressed sequence AI462167,
  • Tgif,
  • MGI:2146782,
  • AA959811,
  • TGFB-induced factor homeobox 1,
  • expressed sequence AA959811,
  • MGI:2146872,
  • AI462167,
  • Tgif1,
  • TG interacting factor
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