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Protein Coding Gene : Haao 3-hydroxyanthranilate 3,4-dioxygenase
Primary Identifier  MGI:1349444 Organism  mouse, laboratory
Chromosome  17 NCBI Gene Number  107766
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables 3-hydroxyanthranilate 3,4-dioxygenase activity. Predicted to be involved in several processes, including carboxylic acid metabolic process; response to cadmium ion; and response to zinc ion. Predicted to be located in cytosol and mitochondrial membrane. Predicted to be active in cytoplasm. Is expressed in ductus deferens; epididymis; esophagus; metanephros; and testis. Orthologous to human HAAO (3-hydroxyanthranilate 3,4-dioxygenase).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced LPS-induced depressive behaviors and altered kynurenine metabolism. [provided by MGI curators]
  • synonyms:
  • 3-hydroxyanthranilate 3,4-dioxygenase,
  • 0610012J07Rik,
  • RIKEN cDNA 0610012J07 gene,
  • 3HAO,
  • MGI:1918919,
  • RIKEN cDNA 0610007K21 gene,
  • Haao,
  • 3-HAO,
  • 3-HAOxase,
  • 0610007K21Rik,
  • MGI:1913307
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