Primary Identifier | MGI:99462 | Organism | mouse, laboratory |
Chromosome | 17 | NCBI Gene Number | 18701 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable phosphotransferase activity, for other substituted phosphate groups. Involved in GPI anchor biosynthetic process. Located in endoplasmic reticulum membrane. Is expressed in several structures, including alimentary system; brain; respiratory system; sensory organ; and urinary system. Orthologous to human PIGF (phosphatidylinositol glycan anchor biosynthesis class F). PHENOTYPE: Mice homozygous for a knock-out allele exhibit abnormal placenta morphology and complete lethality throughout fetal growth and development. [provided by MGI curators] |