| Primary Identifier | MGI:2687286 | Organism | mouse, laboratory |
| Chromosome | 18 | NCBI Gene Number | 210719 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in muscle organ development and positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including collagen fibril organization; regulation of biosynthetic process; and tendon development. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; embryo mesenchyme; genitourinary system; limb; and sensory organ. Orthologous to human MKX (mohawk homeobox). PHENOTYPE: Mice homozygous for a knock-out allele exhibit thin, hypoplastic tendons with reduced tensile strength. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
