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Protein Coding Gene : Cables1 CDK5 and Abl enzyme substrate 1
Primary Identifier  MGI:1927065 Organism  mouse, laboratory
Chromosome  18 NCBI Gene Number  63955
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Acts upstream of or within nervous system development. Predicted to be located in nucleoplasm. Predicted to be active in cytosol. Is expressed in several structures, including central nervous system; genitourinary system; liver; retina; and vibrissa. Orthologous to human CABLES1 (Cdk5 and Abl enzyme substrate 1).
PHENOTYPE: Homozygous null females exhibited reduced fertility and uterine hyperplasia. With chronic exposure to estrogen, homozygous females develop endometrial adenocarcinoma. [provided by MGI curators]
  • synonyms:
  • interactor-1 with cdk3,
  • ik3-1,
  • Cables1,
  • CDK5 and Abl enzyme substrate 1
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Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

7 Pathways

Trail: ProteinCodingGene

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For





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