| Primary Identifier | MGI:1098233 | Organism | mouse, laboratory |
| Chromosome | 18 | NCBI Gene Number | 16210 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables actin binding activity; protein sequestering activity; and ribosome binding activity. Involved in several processes, including GCN2-mediated signaling; cellular response to amino acid starvation; and regulation of gene expression. Acts upstream of or within negative regulation of protein phosphorylation and regulation of translational initiation. Located in cytoplasm. Is expressed in several structures, including brain; extraembryonic component; genitourinary system; gut; and hemolymphoid system gland. Orthologous to human IMPACT (impact RWD domain protein). PHENOTYPE: Mice homozygous for a null mutation display resistance to high fat diet induced obesity and reduced body temperature and glucose levels after fasting. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
