| Primary Identifier | MGI:1929211 | Organism | mouse, laboratory |
| Chromosome | 18 | NCBI Gene Number | 56515 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein kinase binding activity; single-stranded DNA binding activity; and ubiquitin protein ligase activity. Acts upstream of or within cellular response to leukemia inhibitory factor. Predicted to be active in site of double-strand break. Is expressed in several structures, including genitourinary system; lung; nervous system; sensory organ; and tooth. Orthologous to human RNF138 (ring finger protein 138). PHENOTYPE: Homozygous null males show increased spermatogenic cell apoptosis, loss of proliferative spermatogonia, delayed development of spermatozoa and impaired fertility. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
