Primary Identifier | MGI:99179 | Organism | mouse, laboratory |
Chromosome | 18 | NCBI Gene Number | 22694 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within inflammatory response to antigenic stimulus and negative regulation of T-helper 2 cell differentiation. Predicted to be active in nucleus. Is expressed in several structures, including bladder; central nervous system; early conceptus; and gonad. PHENOTYPE: Mice homozygous for a knock-out mutation exhibit increased airway responsiveness to ovalbumin and methacholine. [provided by MGI curators] |