| Primary Identifier | MGI:3584514 | Organism | mouse, laboratory |
| Chromosome | 18 | NCBI Gene Number | 574402 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable G protein-coupled receptor activity and receptor serine/threonine kinase binding activity. Acts upstream of or within negative regulation of inflammatory response to antigenic stimulus. Predicted to be active in plasma membrane. Is expressed in central nervous system; gut; and male reproductive gland or organ. Orthologous to human GPR17 (G protein-coupled receptor 17). PHENOTYPE: Mice homozygous for a null allele exhibit early differentiation of oligodendroglial progenitor cells and increased myelination without any behavioral or motor deficits. Homozygotes for a different null allele show increased vascular permeability in IgE-dependent passive cutaneous anaphylaxis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
