Primary Identifier | MGI:2447834 | Organism | mouse, laboratory |
Chromosome | 18 | NCBI Gene Number | 225358 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable GTPase activator activity. Predicted to be involved in signal transduction. Is expressed in several structures, including brain; genitourinary system; gut; hemolymphoid system; and integumental system. Orthologous to human FAM13B (family with sequence similarity 13 member B). PHENOTYPE: Mice homozygous for a knock-out allele exhibit normal heart size and do not develop spontaneous arrhythmia but show increased P-wave duration and QT interval and increased susceptibility to pacing-induced atrial and ventricular arrhythmias. [provided by MGI curators] |