Primary Identifier | MGI:88350 | Organism | mouse, laboratory |
Chromosome | 18 | NCBI Gene Number | 12532 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable WW domain binding activity; protein kinase binding activity; and protein tyrosine phosphatase activity. Predicted to be involved in G2/M transition of mitotic cell cycle; positive regulation of G2/M transition of mitotic cell cycle; and positive regulation of G2/MI transition of meiotic cell cycle. Located in mitochondrial intermembrane space and nucleus. Is expressed in several structures, including gonad; hemolymphoid system gland; liver; placenta; and telencephalon. Human ortholog(s) of this gene implicated in endometrial cancer and prostate cancer. Orthologous to human CDC25C (cell division cycle 25C). PHENOTYPE: Mice homozygous for a targeted null mutation exhibit no discernable phenotype; mice are viable and fertile with normal T and B lymphocyte development and proliferative responses. [provided by MGI curators] |