| Primary Identifier | MGI:1914449 | Organism | mouse, laboratory |
| Chromosome | 18 | NCBI Gene Number | 67199 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable amyloid-beta binding activity; protein folding chaperone; and unfolded protein binding activity. Acts upstream of or within B cell activation; actin cytoskeleton organization; and brain development. Is active in centrosome. Is expressed in limb and limb mesenchyme. Orthologous to human PFDN1 (prefoldin subunit 1). PHENOTYPE: Mice homozygous for a gene trapped allele display reduced birth size, slow weight gain, loss of neuron tracts in the brain, uncoordinated movement, impaired B and T cell development and function, mucus clearance defects, hydrocephaly, and premature deathpreceded by physical wasting. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
