Primary Identifier | MGI:1346348 | Organism | mouse, laboratory |
Chromosome | 18 | NCBI Gene Number | 24074 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables histone acetyltransferase binding activity. Acts upstream of or within estrogen receptor signaling pathway; regulation of transcription by RNA polymerase II; and transcription by RNA polymerase II. Located in cytoplasm and male germ cell nucleus. Part of transcription factor TFIID complex. Is expressed in blastocyst; brain; genitourinary system; and tail. Orthologous to human TAF7 (TATA-box binding protein associated factor 7). PHENOTYPE: Mice homozygous for a knock-out allele exhibit embryonic lethality between E3.5 and E5.5. Mice homozygous for a conditional allele activated in thymocytes exhibit impaired T cell differentiation. [provided by MGI curators] |