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Protein Coding Gene : Dpysl3 dihydropyrimidinase-like 3
Primary Identifier  MGI:1349762 Organism  mouse, laboratory
Chromosome  18 NCBI Gene Number  22240
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables phosphoprotein binding activity. Acts upstream of or within nervous system development. Predicted to be located in several cellular components, including cell body; growth cone; and lamellipodium. Predicted to be part of filamentous actin. Predicted to be active in cytosol and synapse. Predicted to colocalize with exocytic vesicle. Is expressed in several structures, including alimentary system; genitourinary system; heart; nervous system; and sensory organ. Orthologous to human DPYSL3 (dihydropyrimidinase like 3).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired axon extension, abnormal neuron growth cones morphology and impaired anterograde transportation. [provided by MGI curators]
  • synonyms:
  • Dpysl3,
  • unc-33-like phosphoprotein,
  • MGI:1924595,
  • CRMP-4,
  • CRMP4,
  • dihydropyrimidinase-like 3,
  • MGI:108043,
  • MGD-MRK-37079,
  • TUC4,
  • RIKEN cDNA 9430041P20 gene,
  • 9430041P20Rik,
  • Ulip1,
  • Ulip
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