Primary Identifier | MGI:105925 | Organism | mouse, laboratory |
Chromosome | 18 | NCBI Gene Number | 12583 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables cysteine dioxygenase activity and transition metal ion binding activity. Predicted to be involved in several processes, including L-cysteine catabolic process; lactation; and response to glucagon. Predicted to act upstream of or within L-cysteine catabolic process to taurine. Located in cytosol. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human CDO1 (cysteine dioxygenase type 1). PHENOTYPE: Mice homozygous for a deletion of this gene show increased preweaning mortality, lower body weight, behavioral defects, skeletal defects, homeostatic and reproductive defects. [provided by MGI curators] |