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Protein Coding Gene : Marchf3 membrane associated ring-CH-type finger 3
Primary Identifier  MGI:2443667 Organism  mouse, laboratory
Chromosome  18 NCBI Gene Number  320253
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable ubiquitin-protein transferase activity. Predicted to be involved in protein ubiquitination. Predicted to be located in endosome and lysosome. Is expressed in several structures, including alimentary system; brain; eye; genitourinary system; and integumental system. Orthologous to human MARCHF3 (membrane associated ring-CH-type finger 3).
PHENOTYPE: Homozygous knockout causes de-repression of interleukin 1 beta activity, which results in increased cytokine levels and increased susceptibility to infection-induced mortality. [provided by MGI curators]
  • synonyms:
  • MGI:1917973,
  • A530081L18Rik,
  • AI843639,
  • MGI:6368851,
  • 6330411I15Rik,
  • RIKEN cDNA 6330411I15 gene,
  • membrane associated ring-CH-type finger 3,
  • March3,
  • membrane-associated ring finger (C3HC4) 3,
  • Marchf3,
  • RIKEN cDNA A530081L18 gene,
  • MGI:2147267,
  • expressed sequence AI843639
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1 Involved In Mutations

Trail: ProteinCodingGene

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