Primary Identifier | MGI:2676828 | Organism | mouse, laboratory |
Chromosome | 18 | NCBI Gene Number | 387161 |
Mgi Type | miRNA gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within with a positive effect on hematopoietic stem cell proliferation. Acts upstream of or within with a negative effect on gene expression. Acts upstream of or within several processes, including blood vessel development; negative regulation of signal transduction; and regulation of primary metabolic process. Located in synapse. Is expressed in several structures, including alimentary system; liver; and retina. Orthologous to human MIR143 (microRNA 143). PHENOTYPE: Homozygous null mice exhibit decreased blood pressure, reduced neointimal thickening and decreased medial thickness following carotid artery ligation. [provided by MGI curators] |