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Protein Coding Gene : St8sia3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
Primary Identifier  MGI:106019 Organism  mouse, laboratory
Chromosome  18 NCBI Gene Number  20451
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity. Involved in ganglioside biosynthetic process and sialylation. Predicted to be located in Golgi membrane. Is expressed in brain; cortical plate; and testis. Orthologous to human ST8SIA3 (ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3).
PHENOTYPE: Homozygous knockout affects sialylation of N- and O-glycans in the striatum. [provided by MGI curators]
  • synonyms:
  • MGD-MRK-33701,
  • MGI:2147270,
  • AI847333,
  • Siat8c,
  • ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3,
  • St8sia3,
  • sialyltransferase 8 (alpha-2, 8-sialyltransferase) C,
  • ST8SiaIII,
  • expressed sequence AI847333
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