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Protein Coding Gene : Pias2 protein inhibitor of activated STAT 2

Primary Identifier  MGI:1096566 Organism  mouse, laboratory
Chromosome  18 NCBI Gene Number  17344
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables several functions, including RNA polymerase II-specific DNA-binding transcription factor binding activity; SUMO transferase activity; and ubiquitin protein ligase binding activity. Acts upstream of or within DNA-templated transcription; protein sumoylation; and regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including branchial arch; central nervous system; early conceptus; embryo mesenchyme; and genitourinary system. Orthologous to human PIAS2 (protein inhibitor of activated STAT 2).
PHENOTYPE: An uncharacterized gene trap insertion does not result in an obvious phenotype although abnormalities are reported in the testes. [provided by MGI curators]
  • synonyms:
  • AI462206,
  • Miz1,
  • ARIP3,
  • RIKEN cDNA 6330408K17 gene,
  • Pias2,
  • PIASxalpha,
  • Msx-interacting-zinc finger,
  • Dib,
  • PIASxbeta,
  • expressed sequence AI462206,
  • expressed sequence AU018068,
  • 6330408K17Rik,
  • PIASxb,
  • MGI:1917978,
  • protein inhibitor of activated STAT 2,
  • MGI:2147299,
  • AU018068,
  • MGI:2147235

Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

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1 Involved In Mutations

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

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Expression

Gene --> Expression annotations

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Disease

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Literature

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