Primary Identifier | MGI:2444951 | Organism | mouse, laboratory |
Chromosome | 18 | NCBI Gene Number | 212163 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable transcription corepressor activity and ubiquitin protein ligase activity. Predicted to be involved in negative regulation of viral life cycle and ubiquitin-dependent protein catabolic process. Predicted to be located in chromatin. Orthologous to human ARK2N (arkadia (RNF111) N-terminal like PKA signaling regulator 2N). PHENOTYPE: Mice homozygous for a null allele exhibit reduced skeletal muscle fiber size, exercise capacity, and muscle contractile function, and increased adiposity. [provided by MGI curators] |