Primary Identifier | MGI:1351653 | Organism | mouse, laboratory |
Chromosome | 18 | NCBI Gene Number | 27411 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables urea transmembrane transporter activity. Predicted to be involved in urea transmembrane transport. Located in apical plasma membrane and basolateral plasma membrane. Is expressed in metanephros and nervous system. Orthologous to human SLC14A2 (solute carrier family 14 member 2). PHENOTYPE: Homozygous mice lacking the collecting duct specific isoforms display decreased urea permeability and urine osmolality and increased urine flow. [provided by MGI curators] |