| Primary Identifier | MGI:2685179 | Organism | mouse, laboratory |
| Chromosome | 18 | NCBI Gene Number | 240476 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Predicted to enable DNA-binding transcription factor activity and transcription cis-regulatory region binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be active in nucleus. Is expressed in extraembryonic component; primitive endoderm; and yolk sac. Orthologous to human ZNF407 (zinc finger protein 407). PHENOTYPE: Mice homozygous for a knock-out allele exhibit failure of blastocyst formation and complete embryonic lethality before implantation. In vitro, embryos fail to hatch from the zona pellucida and show no further development after 3 days in culture. [provided by MGI curators] |